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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
EUroHospitalopressureCialisToprol XLPharmacyPharmacyUAEProtect CONS - Efficacy Analysis Callouses: For those who are insured, the table below provides a summary of the2017 CONS - Efficacy Analysis Callouses table
    Restores A Patient's Blood Pressure Levels: This table provides a summary of the impact of Cialis on the blood pressure level and the associated stress. For those taking Cialis with a lower blood pressure medication, this table provides a summary of the impact of the medication on the blood pressure level and the associated stress.

U. S. National Library of Medicine - View full Ref Ref Available in: https://www.ncbi.nlm.nih.gov/books/NBK441996/

For those taking Cialis with nitrates or nitroglycerin, see the “Nitrates and Their Phosphodiesterase 5” table below:

  1. Nitrates (e.g.

Erectile dysfunction is a very common condition that affects many men. It’s one of the most common reasons for anxiety, depression, and even heart disease. Fortunately, there are many ways to treat ED and make it a priority. With the help of a number of effective medications available, ED can be effectively treated. One such medication is Tadalafil. Tadalafil works by relaxing the blood vessels in the penis, allowing for increased blood flow. This helps men to achieve and maintain an erection. Another effective medication is Cialis. This medication works by increasing the amount of blood flow in the penis. It is one of the most well-known medications for ED. It works by relaxing the muscles in the penis, allowing for increased blood flow. Another medication that can be used for ED is Viagra. Viagra works by increasing the amount of blood flow in the penis, allowing for an erection. It is also known for its effectiveness in treating the symptoms of erectile dysfunction. The medication is also known for its effectiveness in treating the symptoms of premature ejaculation. This medication is also known for its effectiveness in treating the symptoms of erectile dysfunction. When taking the medication, it is important to follow the instructions provided by your healthcare provider. This medication should be taken about one hour before sexual activity. The medication can help to improve sexual satisfaction for men. It is also important to note that it is not recommended to take the medication with alcohol. If you have any concerns or questions about this medication, please reach out to us.

VIDEO

How does Tadalafil work?

Tadalafil, also known as Cialis, is a medication that is available as a prescription drug. It works by relaxing the blood vessels in the penis, allowing for increased blood flow. This allows men to achieve and maintain an erection. It works by increasing the amount of blood flow in the penis, allowing for an erection. It is also known for its effectiveness in treating the symptoms of premature ejaculation.

What are the uses of Tadalafil?

The use of Tadalafil is to help men achieve and maintain a strong erection for sexual activity. It can be used for:

  • Men with erectile dysfunction
  • Men taking nitrates for chest pain or heart conditions
  • Men who have taken nitroglycerin in the past, but are now taking this medication

Tadalafil is also used to treat symptoms of benign prostatic hyperplasia (BPH). This medication can help to improve the flow of urine into the bladder. This medication is also used to treat ED, as well as other medical conditions. It is important to note that it is not recommended to take this medication with alcohol. It is also important to note that it is not recommended to take the medication with grapefruit juice. It is also important to note that Tadalafil can also be used to treat high blood pressure.

Is Tadalafil safe to take?

Tadalafil is safe to take if you are taking nitrates. It can be taken with or without food. Tadalafil can also be taken with or without food. If you are taking nitrates for chest pain, your doctor may suggest a lower dose of Tadalafil. It is important to note that it is not recommended to take this medication with grapefruit juice. It is also not recommended to take this medication with grapefruit juice.

Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

  • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
  • Your doctor may recommend taking generic Cialis regularly, once a day.

Follow your doctors instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Cialis 1mg Tablets 10 Tablets (W-Glide)Ingredients: Cialis 1mg tablets are for use in men only. Cialis 1mg tablets are for use in men only.Cialis 1mg Tablets 20 Tablets (W-Glide)Ingredients: Cialis 1mg tablets are for use in men only.Dosage: 5 or 10 mg Cialis 1mg tablets are for use in men only.References
  1. Molek & Schälensch service,, March 19, 2021. "Cialis for men: a guide for doctors and patients". Molagen, Switzerland, GmbH & Co. P. 200131.
  2. Lederle Pharmaceuticals,, June 11, 2018. "Tadalafil in men's health: clinical effectiveness, safety, and common side effects".Cialis Daily,, June 28, 2018.
  3. H. Lee,, May 8, 2017. "Cialis: A guide for doctors and patients".
  4. Cialis,, December 11, 2017, "Cialis: Clinical effectiveness, safety, and common side effects".

Last updated: 2025-01-08

Cialis Daily review.
  • M. Stübener,, "Cialis (tadalafil) – a guide for doctors and patients".
  • J. K.
  • 2023-08-12

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